兔抗CABLES1多克隆抗体

Background:

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB

Name of antibody:

CABLES1

Immunogen:

Fusion protein of human CABLES1

Full name:

Cdk5 and Abl enzyme substrate 1

Synonyms：

CABL1; IK3-1; CABLES; HsT2563

SwissProt:

Q8TDN4

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

68 kDa

WB Positive control:

Mouse brain and human fetal muscle tissue, mouse heart tissue

WB Recommended dilution:

500-2000