兔抗CA3多克隆抗体

Background:

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns.

Applications:

ELISA, WB, IHC

Name of antibody:

CA3

Immunogen:

Fusion protein of human CA3

Full name:

carbonic anhydrase 3

Synonyms:

Car3; CAIII

SwissProt:

P07451

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer

IHC Recommend dilution:

100-200

WB Predicted band size:

30 kDa

WB Positive control:

Human liver tissue, Mouse skeletal muscle tissue and Rat skeletal muscle tissue lysates

WB Recommended dilution:

1000-5000