兔抗BUB1多克隆抗体

Background:

This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

BUB1

Immunogen:

Fusion protein of human BUB1

Full name:

BUB1 mitotic checkpoint serine/threonine kinase

Synonyms：

BUB1A; BUB1L; hBUB1

SwissProt:

O43683

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human brain and human thyroid cancer

IHC Recommend dilution:

50-200