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中文名称：兔抗BTK(Ab-222) 多克隆抗体
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Background: |
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. |
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Applications: |
WB, IHC |
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Name of antibody: |
BTK(Ab-222) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human BTK around the phosphorylation site of tyrosine 222 (A-L-Y(p)-D-Y). |
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Full name: |
Bruton agammaglobulinemia tyrosine kinase |
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Synonyms： |
AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK1 |
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SwissProt: |
Q06187 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
76 kDa |
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WB Positive control: |
Hela cells lysate |
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WB Recommended dilution: |
500-3000 |
