中文名称:兔抗BRAF多克隆抗体
Background: |
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
BRAF |
Immunogen: |
Synthetic peptide of human BRAF |
Full name: |
v-raf murine sarcoma viral oncogene homolog B |
Synonyms: |
NS7; BRAF1; RAFB1; B-RAF1 |
SwissProt: |
P15056 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human cervical cancer and Human prostate cancer |
IHC Recommend dilution: |
50-200 |
WB Predicted band size: |
84 kDa |
WB Positive control: |
Hela and Raji cells |
WB Recommended dilution: |
500-2000 |