兔抗BPGM多克隆抗体

Background:

2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Applications:

ELISA, WB, IHC

Name of antibody:

BPGM

Immunogen:

Full length fusion protein

Full name:

bisphosphoglycerate mutase

Synonyms:

DPGM

SwissProt:

P07738

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and Human esophagus cancer

IHC Recommend dilution:

50-300

WB Predicted band size:

30 kDa

WB Positive control:

Human placenta tissue lysate

WB Recommended dilution:

1000-5000