兔抗BMX多克隆抗体

Background:

This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Applications:

ELISA, IHC

Name of antibody:

BMX

Immunogen:

Fusion protein of human BMX

Full name:

BMX non-receptor tyrosine kinase

Synonyms：

ETK; PSCTK2; PSCTK3

SwissProt:

P51813

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human cervical cancer

IHC Recommend dilution:

50-200