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Background: |
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. |
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Applications: |
WB |
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Name of antibody: |
BMX(Phospho-Tyr566) |
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Immunogen: |
Peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y(p)-V-S) derived from Human ETK. |
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Full name: |
BMX non-receptor tyrosine kinase |
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Synonyms： |
ETK; PSCTK2; PSCTK3 |
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SwissProt: |
P51813 |
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WB Predicted band size: |
78 kDa |
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WB Positive control: |
Hela cells lysates treated with Serum |
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WB Recommended dilution: |
500-1000 |
