兔抗BHMT2多克隆抗体

Background:

Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

BHMT2

Immunogen:

Fusion protein of human BHMT2

Full name:

betaine--homocysteine S-methyltransferase 2

SwissProt:

Q9H2M3

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer;Human colorectal cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

40 kDa

WB Positive control:

Human kidney tissue lysate

WB Recommended dilution:

500-2000