中文名称:兔抗BGLAP多克隆抗体
Background: |
Bone gamma-carboxyglutamic acid (Gla) protein, known as BGLAP, BGP or osteocalcin, is an abundant, non-collagenous protein component of bone that is produced by osteoblasts. In mice, osteocalcin is composed of a cluster of 3 genes known as OG1, OG2 and ORG, all of which can be found within a 23Kb span of genomic DNA. Human osteocalcin is a highly conserved, 46-50 amino acid, single chain protein that contains three vitamin K-dependent g-carboxyglutamic acid residues. Osteocalcin appears transiently in embryonic bone at the time of mineral deposition, where it binds to hydroxyapatite in a calcium-dependent manner. |
Applications: |
ELISA, IHC |
Name of antibody: |
BGLAP |
Immunogen: |
Synthetic peptide of human BGLAP |
Full name: |
bone gamma-carboxyglutamate (gla) protein |
Synonyms: |
OC; BGP; OCN |
SwissProt: |
P02818 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human thyroid cancer and Human brain |
IHC Recommend dilution: |
50-200 |