中文名称:兔抗BCR(Phospho-Tyr360)多克隆抗体
Background: |
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. |
Applications: |
WB |
Name of antibody: |
BCR(Phospho-Tyr360) |
Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 360 (T-T-Y(p)-R-M) derived from Human Bcr. |
Full name: |
breakpoint cluster region |
Synonyms: |
ALL; CML; PHL; BCR1; D22S11; D22S662 |
SwissProt: |
P11274 |
WB Predicted band size: |
143 kDa |
WB Positive control: |
COS7 cells lysates |
WB Recommended dilution: |
500-1000 |