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中文名称：兔抗BCAR1(Phospho-Tyr410)多克隆抗体
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Background: |
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion. Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells. |
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Applications: |
WB, IHC |
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Name of antibody: |
BCAR1(Phospho-Tyr410) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas . |
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Full name: |
breast cancer anti-estrogen resistance 1 |
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Synonyms： |
CAS; CAS1; CASS1; CRKAS; P130Cas |
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SwissProt: |
P56945 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
93 kDa |
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WB Positive control: |
K562 cells and NIH/3T3 cells lysates |
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WB Recommended dilution: |
500-1000 |
