中文名称:兔抗BAX(Ab-167)多克隆抗体
Background: |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. |
Applications: |
WB, IF |
Name of antibody: |
BAX(Ab-167) |
Immunogen: |
Synthesized non-phosphopeptide derived from human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T). |
Full name: |
BCL2-associated X protein |
Synonyms: |
BCL2L4 |
SwissProt: |
Q07812 |
WB Predicted band size: |
21 kDa |
WB Positive control: |
HepG2 cells lysate |
WB Recommended dilution: |
500-3000 |
IF positive control: |
LOVO cells |
IF Recommend dilution: |
100-500 |