兔抗B4GALT3多克隆抗体

Background:

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Applications:

WB, IHC

Name of antibody:

B4GALT3

Immunogen:

Synthesized peptide derived from internal of human B4GALT3.

Full name:

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3

Synonyms：

beta4Gal-T3

SwissProt:

O60512

IHC positive control:

Human liver carcinoma tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

44 kDa

WB Positive control:

HepG2 cells, Hela cells and Jurkat cells lysates

WB Recommended dilution:

500-3000