兔抗AVPR1B多克隆抗体

Background:

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.

Applications:

ELISA, IHC

Name of antibody:

AVPR1B

Immunogen:

Synthetic peptide of human AVPR1B

Full name:

arginine vasopressin receptor 1B

Synonyms:

AVPR3

SwissProt:

P47901

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

10-50