兔抗AUP1多克隆抗体

Background:

This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.

Applications:

ELISA, WB, IHC

Name of antibody:

AUP1

Immunogen:

Fusion protein of human AUP1

Full name:

ancient ubiquitous protein 1

SwissProt:

Q9Y679

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human lung cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

53 kDa

WB Positive control:

Hela and 293T cells

WB Recommended dilution:

500-2000