中文名称:兔抗ATXN3多克隆抗体
Background: |
Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: |
WB |
Name of antibody: |
ATXN3 |
Immunogen: |
Fusion protein of human ATXN3 |
Full name: |
ataxin 3 |
Synonyms: |
ATXN3; AT3; ATX3; JOS; MJD; MJD1; SCA3 |
SwissProt: |
P54252 |
WB Predicted band size: |
43 kDa |
WB Positive control: |
MCF7 cells |
WB Recommended dilution: |
500-2000 |