兔抗ATXN3多克隆抗体

Background:

Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

WB

Name of antibody:

ATXN3

Immunogen:

Fusion protein of human ATXN3

Full name:

ataxin 3

Synonyms：

ATXN3; AT3; ATX3; JOS; MJD; MJD1; SCA3

SwissProt:

P54252

WB Predicted band size:

43 kDa

WB Positive control:

MCF7 cells

WB Recommended dilution:

500-2000