中文名称:兔抗ATP6V1H多克隆抗体
Background: |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular organelles. V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. The encoded protein is the regulatory H subunit of the V1 domain of V-ATPase, which is required for catalysis of ATP but not the assembly of V-ATPase. Decreased expression of this gene may play a role in the development of type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Applications: |
IHC |
Name of antibody: |
ATP6V1H |
Immunogen: |
Synthesized peptide derived from internal of human ATP6V1H. |
Full name: |
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H |
Synonyms: |
SFD; NBP1; VMA13; CGI-11; MSTP042; SFDbeta; SFDalpha |
SwissProt: |
Q9UI12 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |