Background: |
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. |
Applications: |
ELISA, IHC |
Name of antibody: |
WDFY3 |
Immunogen: |
Fusion protein of human WDFY3 |
Full name: |
WD repeat and FYVE domain containing 3 |
Synonyms: |
ALFY; ZFYVE25 |
SwissProt: |
Q8IZQ1 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human thyroid cancer and human prostate cancer |
IHC Recommend dilution: |
25-100 |