Background: |
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria. |
Applications: |
WB |
Name of antibody: |
WAS |
Immunogen: |
Synthetic peptide of human WAS |
Full name: |
Wiskott-Aldrich syndrome |
Synonyms: |
THC; IMD2; SCNX; THC1; WASP |
SwissProt: |
P42768 |
WB Predicted band size: |
53 kDa |
WB Positive control: |
Hela, Jurkat and Raji cells |
WB Recommended dilution: |
500-1000 |