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021-54845833/15800441009
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Background: |
This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
VAC14 |
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Immunogen: |
Fusion protein of human VAC14 |
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Full name: |
VAC14 component of PIKFYVE complex |
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Synonyms: |
TRX; TAX1BP2; ArPIKfyve |
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SwissProt: |
Q08AM6 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human breast cancer |
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IHC Recommend dilution: |
100-200 |
