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Background: |
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TPH1 |
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Immunogen: |
Fusion protein of human TPH1 |
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Full name: |
tryptophan hydroxylase 1 |
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Synonyms： |
TPRH; TRPH |
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SwissProt: |
P17752 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human thyroid cancer and human gastric cancer |
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IHC Recommend dilution: |
15-50 |
