Background: |
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
TP53BP2 |
Immunogen: |
Synthetic peptide of human TP53BP2 |
Full name: |
tumor protein p53 binding protein, 2 |
Synonyms: |
BBP, 53BP2, ASPP2, P53BP2, PPP1R13A |
SwissProt: |
Q13625 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human colon cancer and Human gastric cancer |
IHC Recommend dilution: |
10-50 |