Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. |
Applications: |
ELISA, WB |
Name of antibody: |
TNFRSF21 |
Immunogen: |
Synthetic peptide of human TNFRSF21 |
Full name: |
tumor necrosis factor receptor superfamily, member 21 |
Synonyms: |
DR6, CD358, BM-018 |
SwissProt: |
O75509 |
ELISA Recommended dilution: |
1000-10000 |
WB Predicted band size: |
72 kDa |
WB Positive control: |
Human fetal brain tissue |
WB Recommended dilution: |
500-2000 |