兔抗TMED1多克隆抗体

Background:

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Applications:

ELISA, WB, IHC

Name of antibody:

TMED10

Immunogen:

Fusion protein of human TMED10

Full name:

transmembrane p24 trafficking protein 10

Synonyms:

p23; TMP21; p24d1; S31I125; Tmp-21-I; S31III125; P24(DELTA)

SwissProt:

P49755

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human lung cancer and Human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

25 kDa

WB Positive control:

NIH/3T3 cell, Mouse Pancreas tissue, Rat lung tissue, Mouse liver tissue, Hela, Raji cell lysates

WB Recommended dilution:

1000-5000