Background: |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES By similarity. |
Applications: |
WB |
Name of antibody: |
TLE2 |
Immunogen: |
Synthesized peptide derived from internal of human TLE2. |
Full name: |
transducin-like enhancer of split 2 |
Synonyms: |
ESG; ESG2; GRG2 |
SwissProt: |
Q04725 |
WB Predicted band size: |
80 kDa |
WB Positive control: |
LOVO cells lysate |
WB Recommended dilution: |
500-3000 |