Background: |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
TIMP3 |
Immunogen: |
Fusion protein of human TIMP3 |
Full name: |
TIMP metallopeptidase inhibitor 3 |
Synonyms: |
SFD; K222; K222TA2; HSMRK222 |
SwissProt: |
P35625 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer and Human cervical cancer |
IHC Recommend dilution: |
15-50 |
WB Predicted band size: |
24 kDa |
WB Positive control: |
Huvec cells |
WB Recommended dilution: |
200-1000 |