Background: |
The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE). |
Applications: |
ELISA, IHC |
Name of antibody: |
TGM1 |
Immunogen: |
Synthetic peptide of human TGM1 |
Full name: |
transglutaminase 1 |
Synonyms: |
LI; KTG; LI1; TGK; ICR2; ARCI1; TGASE |
SwissProt: |
P22735 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
25-100 |