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Background: |
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. |
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Applications: |
IHC |
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Name of antibody: |
TGFBR2(Phospho-Ser225/250) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 225/250(D-R-S(p)-D-I) derived from Human TGF β Receptor II. |
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Full name: |
transforming growth factor, beta receptor II (70/80kDa) |
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Synonyms： |
AAT3; FAA3; LDS2; MFS2; RIIC; LDS1B; LDS2B; TAAD2; TGFR-2; TGFbeta-RII |
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SwissProt: |
P37173 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
