Background: |
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. |
Applications: |
ELISA, IHC |
Name of antibody: |
TDGF1 |
Immunogen: |
Fusion protein of human TDGF1 |
Full name: |
teratocarcinoma-derived growth factor 1 |
Synonyms: |
CR; CRGF; CRIPTO |
SwissProt: |
P13385 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
40-200 |