Background: |
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. |
Applications: |
WB, IHC |
Name of antibody: |
TCP1 |
Immunogen: |
Fusion protein of human TCP1 |
Full name: |
t-complex 1 |
Synonyms: |
CCT1; CCTa; D6S230E; CCT-alpha; TCP-1-alpha |
SwissProt: |
P17987 |
IHC positive control: |
Human liver cancer and Human prostate cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
60 kDa |
WB Positive control: |
Hela, Jurkat, 231, hepg2 and PC3 cell |
WB Recommended dilution: |
500-2000 |