兔抗TAB3多克隆抗体

Background:

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene.

Applications:

ELISA, WB, IHC

Name of antibody:

TAB3

Immunogen:

Fusion protein of human TAB3

Full name:

TGF-beta activated kinase 1/MAP3K7 binding protein 3

Synonyms：

NAP1; MAP3K7IP3

SwissProt:

Q8N5C8

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human thyroid cancer and human brain

IHC Recommend dilution:

50-200

WB Predicted band size:

79 kDa

WB Positive control:

293T, Raw264.7, NIH/3T3, K562 and Jurkat cells

WB Recommended dilution:

1000-5000