Background: |
This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SYVN1 |
Immunogen: |
Fusion protein of human SYVN1 |
Full name: |
Synovial apoptosis inhibitor 1, synoviolin |
Synonyms: |
DER3; HRD1 |
SwissProt: |
Q86TM6 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer and Human esophagus cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
68 kDa |
WB Positive control: |
Lovo, hela and 293T cells |
WB Recommended dilution: |
200-1000 |