兔抗SULF2多克隆抗体

Background:

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).

Applications:

ELISA, IHC

Name of antibody:

SULF2

Immunogen:

Synthetic peptide of human SULF2

Full name:

sulfatase 2

Synonyms:

HSULF-2

SwissProt:

Q8IWU5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil

IHC Recommend dilution:

20-100