Background: |
The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SUFU |
Immunogen: |
Fusion protein of human SUFU |
Full name: |
SUFU negative regulator of hedgehog signaling |
Synonyms: |
SUFUH; JBTS32; SUFUXL; PRO1280 |
SwissProt: |
Q9UMX1 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer and Human colon cancer |
IHC Recommend dilution: |
15-50 |
WB Predicted band size: |
54 kDa |
WB Positive control: |
Jurkat cells |
WB Recommended dilution: |
200-1000 |