Background: |
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. |
Applications: |
IHC |
Name of antibody: |
STK39(Phospho-Ser325) |
Immunogen: |
Peptide sequence around phosphorylation site of Serine 325(S-K-R(p)-R-T) derived from Human STK39. |
Full name: |
serine threonine kinase 39 |
Synonyms: |
DCHT; PASK; SPAK |
SwissProt: |
Q9UEW8 |
IHC positive control: |
Human brain tissue |
IHC Recommend dilution: |
50-100 |