兔抗APIP多克隆抗体

Background:

APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria.

Applications:

ELISA, WB, IHC

Name of antibody:

APIP

Immunogen:

Fusion protein of human APIP

Full name:

Probable methylthioribulose-1-phosphate dehydratase

Synonyms：

APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2

SwissProt:

Q96GX9

ELISA Recommended dilution:

500-5000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

27 kDa

WB Positive control:

Mouse heart tissue

WB Recommended dilution:

200-1000