Background: |
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. |
Applications: |
WB |
Name of antibody: |
STK10 |
Immunogen: |
Synthesized peptide derived from internal of human STK10. |
Full name: |
serine/threonine kinase 10 |
Synonyms: |
LOK; PRO2729 |
SwissProt: |
O94804 |
WB Predicted band size: |
112 kDa |
WB Positive control: |
Hela cells and Huvec cells lysates |
WB Recommended dilution: |
500-3000 |