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021-54845833/15800441009
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Background: |
Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe3+ to Fe2+. Can also reduce of Cu2+ to Cu1+, suggesting that it participates in copper homeostasis. Uses NADP+ as acceptor. May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP. |
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Applications: |
WB, IF |
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Name of antibody: |
STEAP3 |
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Immunogen: |
Synthesized peptide derived from internal of human STEA3. |
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Full name: |
STEAP family member 3, metalloreductase |
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Synonyms： |
STMP3; TSAP6; AHMIO2; dudlin-2 |
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SwissProt: |
Q658P3 |
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WB Predicted band size: |
55 kDa |
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WB Positive control: |
COLO205 cells lysate |
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WB Recommended dilution: |
500-3000 |
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IF positive control: |
Hela cells |
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IF Recommend dilution: |
100-500 |
