Background: |
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
STARD5 |
Immunogen: |
Synthetic peptide of human STARD5 |
Full name: |
StAR-related lipid transfer (START) domain containing 5 |
SwissProt: |
Q9NSY2 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
40-150 |
WB Predicted band size: |
24 kDa |
WB Positive control: |
Human fetal brain tissue |
WB Recommended dilution: |
500-2000 |