兔抗ST5多克隆抗体

Background:

This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Applications:

WB

Name of antibody:

ST5

Immunogen:

Synthesized peptide derived from internal of human ST5.

Full name:

suppression of tumorigenicity 5

Synonyms：

HTS1; p126; DENND2B

SwissProt:

P78524

WB Predicted band size:

126 kDa

WB Positive control:

COLO205 cells lysate

WB Recommended dilution:

500-3000