Background: |
This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. |
Applications: |
ELISA, IHC |
Name of antibody: |
SRGAP2 |
Immunogen: |
Synthetic peptide of human SRGAP2 |
Full name: |
SLIT-ROBO Rho GTPase activating protein 2 |
Synonyms: |
FNBP2; SRGAP3; SRGAP2A; ARHGAP34 |
SwissProt: |
O75044 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |