Background: |
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance. |
Applications: |
WB |
Name of antibody: |
SRCIN1 |
Immunogen: |
Synthesized peptide derived from internal of human SNIP. |
Full name: |
SRC kinase signaling inhibitor 1 |
Synonyms: |
P140; SNIP |
SwissProt: |
Q9C0H9 |
WB Predicted band size: |
112 kDa |
WB Positive control: |
HepG2 and Hela cells lysates |
WB Recommended dilution: |
500-3000 |