Background: |
This locus encodes a member of the spectrin gene family. Spectrin proteins, along with ankyrin, play a role in cell membrane organization and stability. The protein encoded by this locus functions in stability of erythrocyte membranes, and mutations in this gene have been associated with spherocytosis type 2, hereditary elliptocytosis, and neonatal hemolytic anemia. Alternatively spliced transcript variants have been described. |
Applications: |
ELISA, IHC |
Name of antibody: |
SPTB |
Immunogen: |
Synthetic peptide of human SPTB |
Full name: |
spectrin beta, erythrocytic |
Synonyms: |
EL3; HS2; SPH2; HSPTB1 |
SwissProt: |
P11277 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
25-100 |