Background: |
This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SPRY4 |
Immunogen: |
Full length fusion protein |
Full name: |
sprouty RTK signaling antagonist 4 |
Synonyms: |
HH17 |
SwissProt: |
Q9C004 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human lung cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
33 kDa |
WB Positive control: |
K562,A375 and 231 cell |
WB Recommended dilution: |
500-2000 |