Background: |
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression (By similarity). |
Applications: |
ELISA, IHC |
Name of antibody: |
SPIC |
Immunogen: |
Full length fusion protein |
Full name: |
Spi-C transcription factor (Spi-1/PU.1 related) |
Synonyms: |
SPI-C |
SwissProt: |
Q8N5J4 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
40-250 |