Background: |
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SPARC |
Immunogen: |
Fusion protein of human SPARC |
Full name: |
secreted protein, acidic, cysteine-rich (osteonectin) |
Synonyms: |
ON |
SwissProt: |
P09486 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
35 kDa |
WB Positive control: |
A375 cells |
WB Recommended dilution: |
500-2000 |