兔抗SP1多克隆抗体

Background:

The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

SP1

Immunogen:

Synthetic peptide of human SP1

Full name:

Sp1 transcription factor

SwissProt:

P08047

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and Human ovarian cancer

IHC Recommend dilution:

50-200