Background: |
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein. |
Applications: |
WB |
Name of antibody: |
SNX9 |
Immunogen: |
Fusion protein of human SNX9 |
Full name: |
sorting nexin 9 |
Synonyms: |
SNX9; MST155; MSTP155; SDP1; SH3PX1; SH3PXD3A; WISP |
SwissProt: |
Q9Y5X1 |
WB Predicted band size: |
67 kDa |
WB Positive control: |
HeLa cells |
WB Recommended dilution: |
500-2000 |