Background: |
Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
SNTA1 |
Immunogen: |
Synthetic peptide of human SNTA1 |
Full name: |
syntrophin, alpha 1 |
Synonyms: |
SNT1; LQT12; TACIP1; dJ1187J4.5 |
SwissProt: |
Q13424 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
54 kDa |
WB Positive control: |
Human colon cancer and normal stomach tissue |
WB Recommended dilution: |
200-1000 |